ea0037gp.26.03 | Thyroid – hypothyroidism | ECE2015
de Lloyd Anna
, Muller Ilaria
, Dodd Alan
, Bakhsh Ameen
, Durrant Hilary
, Zhang Lei
, Evans Carol
, Rees Aled
, Ludgate Marian
Introduction: The effects of mild subclinical hypothyroidism (SH; TSH <10 mU/l) on metabolic outcomes are unclear. This may relate to differences in aetiology, including thyroid autoimmunity or genetic factors such as TSH-receptor mutations (TSHR-M) and FOXE1 polyalanine tract length (FOXE1PTL) polymorphisms, which are associated with altered thyroid function. We hypothesised that the metabolic manifestations of SH may depend upon its aetiology.<p class="abstext"...